Sun Kun >> Research

Enthusiastic

Research interests
  • Noninvasive prenatal testing/cancer liquid biopsy
  • Original cancer biomarkers
  • AI-empowered models for early cancer diagnosis
  • LncRNA identification and functional study

Research highlights
  • Trace the tissue origin of the tumor through liquid biopsy
  • Sun et al. PNAS 2015 Oct 6; 112(40):E5503-12.
    Plasma DNA Tissue Mapping

    Sun et al. Genome Res 2019 Mar; 29(3):418-427.
    Orientation-aware CfDNA Fragmentation analysis

  • Molecular basis of cfDNA fragmentation
  • Sun et al. PNAS 2018 May 29; 115(22):E5106-E5114.
    Size-tagged preferred ends

    An et al. Nat Commun 2023 Jan 18; 14(1):287.
    DNAm regulate cfDNA

  • Interactions between YY1 transcription factor and lncRNAs
  • Zhou et al. Nat Commun 2015 Dec 11; 6:10026.
    Linc-Yy1

    Lu et al. EMBO J 2013 Oct 2; 32(19):2575-88.
    Yy1 and Yam-1